Typhus

Common Name(s)

Typhus

Typhus is a general term for a group of diseases passed on by lice, flea, tick, and other insect bites. Types of typhus include epidemic typhus, scrub typhus, murine typhus. Common symptoms of most typhus cases include fever, headache, muscle aches, rapid breathing, and rash. Typhus is uncommon in the United States and can be prevented by avoiding contact with rats and keeping pets treated for ticks and fleas. Usually typhus can be cured with antibiotics.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Typhus" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Typhus" returned 439 free, full-text research articles on human participants. First 3 results:

Characterization of the rhesus macaque (Macaca mulatta) scrub typhus model: Susceptibility to intradermal challenge with the human pathogen Orientia tsutsugamushi Karp.
 

Author(s): Piyanate Sunyakumthorn, Suwit J Somponpun, Rawiwan Im-Erbsin, Tippawan Anantatat, Kemajittra Jenjaroen, Susanna J Dunachie, Eric D Lombardini, Robin L Burke, Stuart D Blacksell, James W Jones, Carl J Mason, Allen L Richards, Nicholas P J Day, Daniel H Paris

Journal:

 

Scrub typhus is an important endemic disease in tropical Asia caused by Orientia tsutsugamushi for which no effective broadly protective vaccine is available. The successful evaluation of vaccine candidates requires well-characterized animal models and a better understanding of the ...

Last Updated: 31 Dec 1969

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Newly Recognized Pediatric Cases of Typhus Group Rickettsiosis, Houston, Texas, USA.
 

Author(s): Timothy Erickson, Juliana da Silva, Melissa S Nolan, Lucila Marquez, Flor M Munoz, Kristy O Murray

Journal: Emerging Infect. Dis.. 2017 12;23(12):2068-2071.

 

An increase in typhus group rickettsiosis and an expanding geographic range occurred in Texas, USA, over a decade. Because this illness commonly affects children, we retrospectively examined medical records from 2008-2016 at a large Houston-area pediatric hospital and identified 36 ...

Last Updated: 31 Dec 1969

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Differences in agricultural activities related to incidence of scrub typhus between Korea and Japan.
 

Author(s): Chang-Jin Ma, Gyung-Jae Oh, Gong-Unn Kang, Jeong Mi Lee, Da-Un Lee, Hae-Sung Nam, So Yeon Ryu, Young-Hoon Lee

Journal:

 

The purpose of this study was to establish a basis for improving or strengthening the preventive strategy against scrub typhus in Korea by comparing and analyzing the difference of prevention behaviors contributing to the occurrence of scrub typhus in Japan and Korea.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Typhus" returned 25 free, full-text review articles on human participants. First 3 results:

Scrub typhus point-of-care testing: A systematic review and meta-analysis.
 

Author(s): Kartika Saraswati, Nicholas P J Day, Mavuto Mukaka, Stuart D Blacksell

Journal:

 

Diagnosing scrub typhus clinically is difficult, hence laboratory tests play a very important role in diagnosis. As performing sophisticated laboratory tests in resource-limited settings is not feasible, accurate point-of-care testing (POCT) for scrub typhus diagnosis would be invaluable ...

Last Updated: 31 Dec 1969

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A review of the global epidemiology of scrub typhus.
 

Author(s): Guang Xu, David H Walker, Daniel Jupiter, Peter C Melby, Christine M Arcari

Journal:

 

Scrub typhus is a serious public health problem in the Asia-Pacific area. It threatens one billion people globally, and causes illness in one million people each year. Caused by Orientia tsutsugamushi, scrub typhus can result in severe multiorgan failure with a case fatality rate ...

Last Updated: 31 Dec 1969

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Estimating the burden of scrub typhus: A systematic review.
 

Author(s): Ana Bonell, Yoel Lubell, Paul N Newton, John A Crump, Daniel H Paris

Journal:

 

Scrub typhus is a vector-borne zoonotic disease that can be life-threatening. There are no licensed vaccines, or vector control efforts in place. Despite increasing awareness in endemic regions, the public health burden and global distribution of scrub typhus remains poorly known.

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Scrub Typhus Antibiotic Resistance Trial
 

Status: Recruiting

Condition Summary: Scrub Typhus

 

Last Updated: 12 Dec 2017

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Scrub Typhus Pediatric Immunology Study
 

Status: Recruiting

Condition Summary: Scrub Typhus

 

Last Updated: 31 Aug 2016

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Scrub Typhus RDT Study
 

Status: Recruiting

Condition Summary: The Prevalence of Scrub Typhus

 

Last Updated: 5 Jan 2018

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